Endocrine Abstracts

Introduction: Premature ovarian insufficiency is characterized by precocious depletion of ovarian follicles, associated with amenorrhea, hypoestrogenism and high gonadotropin levels. It afflicts 1% of the female population and in 5% cases it is due to X chromosome abnormalities.Case report: A 22 year old previously healthy female, presented to the Endocrinology Clinic due to amenorrhea. She had no family history of amenorrhea, her menarche was at age 11 ...

Graves’ disease is one of the multiple autoimmune diseases that have been reported in HIV-infected patients. With the upsurge of highly active anti-retroviral therapy (HAART) the incidence of autoimmune diseases in HIV-infected patients is increasing, especially after immune reconstitution. We present a male, 51-year-old, who started complaining with anxiety, sudoresis and palpitations. The laboratory workout revealed hyperthyroidism: TSH <0.02 μU/ml (0.46–4...

Background: Berardinelli-Seip Congenital Lipodystrophy (BSCL) is a autosomal recessive disorder with only up to 500 reported cases. It is characterized by generalized absence of fat since birth and severe metabolic derangements such as insulin resistance, hyperglycemia and dyslipidemia. Diabetes mellitus generally develops during the second or third decade of life. This is a rare clinical condition, with worldwide prevalence of 1 in 10 million people and incidence of 1:500.000...

Background: Management of obesity and overweight greatly improves glycemic control in type 2 diabetic (T2DM) patients and also provides positive impact in other cardiovascular risk factors in this population.Objectives: Evaluate the impact of weight and weight variability in subclinical inflammation and comorbidities of T2DM patients, over the last decade.Methods: Retrospective study of 1900 patients with T2DM, with a minimum of 2 ...

Introduction: The ‘Atypia of Undetermined Significance/Follicular lesion of Undetermined Significance’ (AUS/FLUS) category of the Bethesda Classification for thyroid nodules fine needle aspiration cytology (FNAC) is reserved for specimens that contain cells with architectural and/or nuclear atypia that is not sufficient to be classified as suspicious or malignant. Our objective is to report our experience in the follow-up and outcome of patients with AUS/FLUS in thyr...

Introduction: Increasing incidence of thyroid cancer might be a consequence of an increase detection of subclinical disease. The aim of this study was to compare the clinical and pathologic characteristics of nonincidentally discovered (NID) thyroid cancer with incidentally discovered (ID) on postoperative pathology.Methods: A retrospective medical record review of 104 patients with thyroid cancer was performed. A group I of 69 patients with NID thyroid ...

Background: Type 2 diabetes and Hipertension are common in obese patients. Bariatric surgery is effective in sustained weight loss, but also improves glycemic and hypertension control. A high percentage of diabetes remission occurs.Methods: Retrospective study of type 2 diabetic patients submitted to bariatric surgery between 2006 and 2013 in a central hospital. Primary endpoint was evaluation of diabetes and hypertension remission, 2 years after surgery...

Introduction: The fine needle aspiration cytology (FNAC) of thyroid nodules is the procedure of choice in the diagnostic approach of nodular thyroid disease. Despite showing a sensitivity of 83% and a specificity of 92%, many of the results are non-diagnostic. One of the factors that can contribute to this number is the proper procedure of the smear.Objective: To compare the FNAC’s results in our team with and without the contribution of an expert C...